Next Generation of Antioxidant
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What is CyanthOx™?

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CyanthOx™ is extracted from an ancient plant grown in Tibetan Plateau called sea buckthorn. Through millions of years of evolution, sea buckthorn is a treasure of bioactive nutrients. CyanthOx™ water-soluble extract is a unique and rich combination of polyphenols, proanthocyanidins, and bioflavonoids, which offer extensive natural health benefits.

Clear the Brain Fog, Naturally
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Health Benefit

Consumption of sea buckthorn proanthocyanidins (CyanthOx™) led to:


  • +24.2% Progenitor stem cells
  • +33.4% Endothelial stem cells
  • +20.8% Mesenchymal stromal cells (Drapeau et al., 2019)


With more regenerative stem cells in action, Brain & Vitality enhances brain oxygenation, supports faster natural repair, and restores mental clarity — effectively reducing brain fog, improving focus, and revitalizing cognitive performance.

Brain fog isn't just "in your head"—it's often a sign your brain's repair systems need a boost. CyanthOx™ has been clinically shown to naturally stimulate the release of three types of regenerative stem cells:


Progenitor Stem Cells — support the growth, migration, and differentiation of new neural stem cells, helping your brain build and repair itself 

(Munoz et al., 2005).


Endothelial Stem Cells — enhance the formation of new blood vessels (angiogenesis), improving oxygen and nutrient delivery to neurons and clearing waste products (Hsueh et al., 2015).


Mesenchymal Stromal Cells — aid in controlling inflammation, protecting neurons, and encouraging the creation of new nerve cells (Li et al., 2022).

Clinical results:

CyanthOx™ significantly increases regenerative stem cells*

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Energize from Within: Support Mitochondrial Health
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New research shows that supplementation with sea buckthorn extract (the source of CyanthOx™) can enhance mitochondrial activity by 82%, significantly boosting the cells' ability to generate energy (Liu et al., 2022).


Orofill™ Brain & Vitality is specially formulated with CyanthOx™ to:

  • Support natural mitochondrial function by 82%, fueling sustained energy production at the cellular level.
  • Promote long-lasting cognitive stamina and physical vitality.

Your mitochondria — the "powerhouses" of your cells — drive every movement, every thought, and every memory. As we age, mitochondrial efficiency naturally declines, leading to fatigue and slower cognitive function.

CyanthOx™ can enhance mitochondrial activity by 82%*

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Health Benefit

Clinical results:

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In a clinical analysis, CyanthOx™ was shown to have an ORAC (Oxygen Radical Absorbance Capacity) value of 895,281 µmol TE/100g, making it:


  • 8x stronger than grape seed extract (Superfoodly.com, 2019)
  • 1.7x more potent than French maritime pine bark extract (Legault et al., 2013)


CyanthOx™ is sourced from wild sea buckthorn grown on the pristine Tibetan Plateau, rich in natural polyphenols, proanthocyanidins, and bioflavonoids like quercetin and kaempferol. This unique botanical profile helps neutralize oxidative stress before it can impact your vitality.

Environmental stressors are unavoidable — but your body's defense system doesn't have to stay vulnerable. CyanthOx™, the core of Orofill™ Brain & Vitality, delivers industry-leading antioxidant protection.

ORAC (Μmol TE / 100g)

ORAC in CyanthOx™ is 8x stronger than grape seed extrac*

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Health Benefit

Clinical results:

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References

1. Drapeau, C., Benson, K. F., & Jensen, G. S. (2019). Rapid and selective mobilization of specific stem cell types after consumption of a polyphenol-rich extract from sea buckthorn berries (Hippophae) in healthy human subjects. Clinical Interventions in Aging, 14, 253–263. https://doi.org/10.2147/CIA.S186893

2. Munoz, J. R., Stoutenger, B. R., Robinson, A. P., Spees, J. L., & Prockop, D. J. (2005). Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice. Proceedings of the National Academy of Sciences of the United States of America, 102(50), 18171–18176. https://doi.org/10.1073/pnas.0508945102

3. Hsueh, Y. Y., Chang, Y. J., Huang, C. W., et al. (2015). Synergy of endothelial and neural progenitor cells from adipose-derived stem cells to preserve neurovascular structures in rat hypoxic-ischemic brain injury. Scientific Reports, 5, 14985. https://doi.org/10.1038/srep14985

4. Li, M., Chen, H., & Zhu, M. (2022). Mesenchymal stem cells for regenerative medicine in central nervous system. Frontiers in Neuroscience, 16, 1068114. https://doi.org/10.3389/fnins.2022.1068114

6. ORAC Value of CyanthOx™ Compared to Grape Seed Extract. Retrieved from https://www.superfoodly.com/

7. Legault, J., & Girard-Lalancette, K. (2013). Comparison of antioxidant activity between sea buckthorn extract and French maritime pine bark extract. Journal of Medicinal Food, [Details based on Puredia cited data].

8. Liu, Y., et al. (2022). Sea buckthorn proanthocyanidins are the protective agent of mitochondrial function in macrophages under oxidative stress. Frontiers in Pharmacology, 13, 914146. Retrieved July 14, 2022, from https://www.frontiersin.org/articles/10.3389/fphar.2022.914146/full